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3,4-Methylenedioxymethamphetamine (MDMA), commonly known as ecstasy (E) or molly, is a psychoactive drug primarily used for recreational purposes.The desired effects include altered sensations, increased energy, empathy, as well as pleasure.When taken by mouth, effects begin in 30 to 45 minutes and last 3 to 6 hours.
MDMA was first developed in 1912 by Merck. It is to enhance psychotherapy beginning in the 70s becomes popular as a street drug . MDMA is commonly with dance parties, raves, and electronic dance music.It may be mixe with other substances such as ephedrine, amphetamine, and methamphetamine. In 2016, about 21 million people between the ages of 15 and 64 used ecstasy (0.3% of the world population).This was broadly similar to the percentage of people who use cocaine or amphetamines, but lower than for cannabis or opioids. In the United States, as of 2017, about 7% of people have used MDMA at some point in their lives and 0.9% have used it in the last year
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Short-term adverse effects include grinding of the teeth, blurred vision, sweating and a rapid heartbeat, and extended use can also lead to addiction, memory problems, paranoia and difficulty sleeping. Deaths is been report due to increase body temperature and dehydration. Following use, people often feel depressed and tired. MDMA acts primarily by increasing the activity of the neurotransmitters serotonin, dopamine and noradrenaline in parts of the brain. It belongs to the substituted amphetamine classes of drugs and has stimulant and hallucinogenic effects.
MDMA is illegal in most countries and, as of 2018, has no approved medical uses.
In general, MDMA users report feeling the onset of subjective effects within 30 to 60 minutes of oral consumption and reaching peak effect at 75 to 120 minutes, which then plateaus for about 3.5 hours.
Buy MDMA Crystals Online. MDMA (3-4 methylenedioxymethamphetamine) is a synthetic, psychoactive drug with a chemical structure similar to the stimulant methamphetamine and the hallucinogen mescaline. MDMA is an illegal drug that acts as both a stimulant and psychedelic, producing an energizing effect, as well as distortions in time and perception and enhanced enjoyment from tactile experiences. It is known commonly as Ecstasy and Molly.
This illicit drug exerts its primary effects in the brain on neurons that use the chemicals serotonin, dopamine and norepinephrine to communicate with other neurons. Serotonin is most likely responsible for the feelings of empathy, elevated mood, and emotional closeness experienced with this drug. Overall, these neurotransmitter systems play an important role in regulating:
energy/activity and the reward system
sensitivity to pain
heart rate, blood pressure.
MDMA was first synthesized by a German company in 1912, possibly to be used as an appetite suppressant. It has been available as a street drug since the 1980s, and use escalated in the 1990s among college students and young adults. Then, it was most often distributed at late-night parties called “raves”, nightclubs, and rock concerts. As the rave and club scene expanded to metropolitan and suburban areas across the country, MDMA use and distribution increased as well. MDMA is frequently used in combination with other drugs. Today, the drug is still used by a broader group of people who more commonly call it Ecstasy or Molly.
Methods of Use
MDMA is most often available in tablet or capsule form and is usually ingested orally. Ecstasy traffickers consistently use brand names and logos as marketing tools and to distinguish their product from that of competitors. The logos may be produced to coincide with holidays or special events. Among the more popular logos are butterflies, lightning bolts, and four-leaf clovers. It is also available as a powder and is sometimes snorted, taken as a liquid, and it is occasionally smoked but rarely injected.
Effects of MDMA Use
MDMA stimulates the release of the neurotransmitters such as serotonin from brain neurons, producing a high that lasts from 3 to 6 hours, but it’s length can be variable based on the user. The drug’s rewarding effects vary with the individual taking it, the dose, purity, and the environment in which it is taken.
MDMA can produce stimulant effects such as an enhanced sense of pleasure and self-confidence and increased energy. Its psychedelic effects include feelings of peacefulness, acceptance, and empathy.
MDMA Health Hazards
Users may encounter problems similar to those experienced by amphetamine and cocaine users, including addiction. Research has shown that animals will self-administer MDMA, an indicator of a drug’s abuse potential.
Damage to brain serotonin neurons can occur; serotonin is thought to play a role in regulating mood, memory, sleep, and appetite. Studies are conflicting on MDMA use and its affects on memory and cognition.
After moderate use of the drug over one week, psychological and physical effects due to withdrawal may include:
agression and impulsiveness
problems with sleep
loss of attention
nausea and decreased appetite
loss of interest in sex
Also, there is evidence that people who develop a rash that looks like acne after using this drug may be at risk of severe side effects, including liver damage, if they continue to use the drug. Almost 60% of people who use Ecstasy report withdrawal symptoms, including fatigue, loss of appetite, depressed feelings, and trouble concentrating.
Drug class: empathogen–entactogen; stimulant
Other names: 3,4-MDMA; Ecstasy (E, X, XTC); Molly; Mandy
Duration of action: 4–6 hours
Onset of action: 30–45 minutes (by mouth)
Metabolism: Liver, CYP450 extensively involved, including CYP2D6
Elimination half-life: (R)-MDMA: 5.8 ± 2.2 hours (variable); (S)-MDMA: 3.6 ± 0.9 hours (variable)